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Pragmatic trials are those that are designed to inform real-world clinical practice. They are typically described as focusing on practical aspects of designing a study which include recruitment and consent, adherence and the use routinely available equipment.
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While Pragmatic Play is known for its slot machines, it also offers table games such as Bitcoin baccarat and Roulette. They offer more than dozen licensed games and their software is renowned for its reliability and security. Their software is available in multiple languages and provide a variety of betting options including live dealer tables.
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Pragmatic Play, one of the most popular iGaming companies offers a wide selection of slot games. Certain games have high RTPs which allow players to maximize their chances of winning. Many of the games are mobile-friendly which means they are suitable for tablets and smartphones. Some of these games include bonus rounds that allow players to win free spins.
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A pragmatic trial that uses different investigators and participants from diverse geographical locations is the Home Blood Pressure Management study (HBPM). This type of heterogeneity which is essential for a pragmatic trial to be reliable and to reduce bias in the results is also essential. A high degree of heterogeneity, however can result in problems with the design of the trial.
Pragmatic Play is also a major player on the live casino market, providing an extensive selection of classic table games such as Blackjack and Roulette in a variety of versions. The company's live studios in Romania and Malta offer a real-life gambling experience for customers and offer a full suite of virtual betting options. The company has also developed numerous interactive game shows that make online gambling enjoyable. Some of these shows have live hosts, while others are hosted by famous personalities from the industry.
Mobile compatibility
Pragmatic Play, a relatively new player in the field of casinos online, has earned an enviable reputation for its mobile-friendly slot machines. Their games are optimized for mobile phones, and are powered by HTML5 technology. They are also certified by trusted gaming authorities to ensure transparency and fairness. This is a good sign for players as it indicates that the games have been tested and validated to ensure randomness and impartiality of every round.
Pragmatic Play offers not only mobile-friendly slot machines as well as table games and live casino. The company is licensed and is regulated by various regulatory bodies that include the Malta Gaming Authority and UK Gambling Commission. The company's games are protected by high-end encryption and its security staff is on hand to assist players in any situation.
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Most Pragmatic Play games are available for free, which means you can play them before deciding to play them with real money. These games can be played on any device including tablets, desktops and mobile phones. You can play them wherever that you connect to the internet. They are easy to navigate. Some Pragmatic Play websites even let you test your luck while on the move by playing a test mode. This allows you to learn about game rules and features before playing with real money.
Legality
Pragmatic Play is renowned for its top-quality games and for providing a superior user experience. Its software is designed to work on mobile devices and is compatible with multiple languages. It has established itself as one of the most popular casino gaming platforms despite its relatively young age. Wolves is one of the latest games, a 5-reel slot machine with a healthy RTP and impressive graphics. The other notable titles include Wolf Gold and Chilli Heat.
The goal of pragmatic trials is to mimic real-life situations and achieve maximum validity externally. They are usually commissioned by practitioners and policy makers to guide their decision-making. They are also a good method to determine the causal relationship between the intervention and its effects. However, they shouldn't be used in lieu for explanatory trials.
The pragmatism concept is controversial, and there are doubts about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 suggested an distinction between explanation-based studies, which confirm the physiological hypothesis or clinical hypothesis, and pragmatic trials, which inform policy and practice decision-making. They also suggested the framework for pragmatic trials, which they called PRECIS.2 This tool was designed to define the features of a pragmatic trial, including the recruitment process, the design and delivery of the intervention, and the follow-up.
There is a positive increase in the number pragmatic trials published. A recent Medline search using the terms pragmatic and naturalistic, restricted to controlled trials randomized to control (RCTs) resulted in 34 articles, which are shown in red in Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatism. However, it is important to remember that the majority of these studies were conducted in primary care settings.